Cyclin-Dependent Kinase 2

A key regulator of CELL CYCLE progression. It partners with CYCLIN E to regulate entry into S PHASE and also interacts with CYCLIN A to phosphorylate RETINOBLASTOMA PROTEIN. Its activity is inhibited by CYCLIN-DEPENDENT KINASE INHIBITOR P27 and CYCLIN-DEPENDENT KINASE INHIBITOR P21.

Also Known As:

CDK2 Protein; Cdc2-Related Protein Kinase; p33cdk2 Kinase; Cdc2 Related Protein Kinase; Cyclin Dependent Kinase 2; Cdk2 Protein Kinase

Enzymes and Coenzymes: 1
- Enzymes: 155591
  - Transferases: 6719
    - Phosphotransferases: 43773
      - Phosphotransferases (Alcohol Group Acceptor)
        Protein Kinases: 9899
        Protein Serine-Threonine Kinases: 3707
        Proline-Directed Protein Kinases: 28
        Cyclin-Dependent Kinases: 4083
        Cyclin-Dependent Kinase 2: 348
Amino Acids, Peptides, and Proteins: 1
- Proteins: 496323
  - Cell Cycle Proteins: 812
    - Cyclin-Dependent Kinases: 4083
      - Cyclin-Dependent Kinase 2: 348
  - Intracellular Signaling Peptides and Proteins: 32
    - Protein Serine-Threonine Kinases: 3707
      - Proline-Directed Protein Kinases: 28
        Cyclin-Dependent Kinases: 4083
        Cyclin-Dependent Kinase 2: 348

Shing S Chan Selected Research

Shing S Chan Research Topics

Disease

Drug/Important Bio-Agent (IBA)